EADS, the European aerospace group, fell 1.8% after losses at its Airbus unit were largely responsible for an 86% drop in 2006 operating profits. The pharmaceuticals sector was led lower after Goldman Sachs lowered its rating on the UK GlaxoSmithKline from neutral to sell. GlaxoSmithKline dropped 1.7%. Meanwhile Novartis, the Swiss drugmaker, fell 2.1% as investors took profits on its recent strong performance.