Biopharmaceutical company Targacept Inc. (TRGT: chart) set its IPO at 6.25 mln shares at an estimated price of $11 to $13 per share.

Winston-Salem, North Carolina-based Targacept is developing drugs to treat diseases and disorders of the central nervous system.

Deutsche Bank Securities, Pacific Growth Equities, CIBC World Markets and Lazard are underwriters for the deal.

The IPO of Dolby Laboratories Inc. (DLB: chart) priced 27.5 million shares at $18, raising $495 million. Of the total shares, 10.5 million shares were sold by Dolby and 17 million shares were sold by Ray Dolby, the company’s founder and principal shareholder. The offering price was originally projected at between $13.50 and $15.50 a share, but was raised after greater market interest

Morgan Stanley, J.P. Morgan and Goldman Sachs led the underwriting.

The company’s shares jumped 38 % in their market debut on the NYSE on Thursday. On Friday the stock closed at $24.57 for a gain of $6.57, or 36.5%.

ECC Capital Corp. (ECR: chart) priced its IPO of 57,189,693 shares at the bottom of the expected price range of $6.75 to $7.25. The Irvine, California-based REIT 's initial public offering raised about $386 million on Monday.

Of the 57.2 million shares in the offering, 52.5 are offered by the company itself and 4.7 are offered by selling stockholders.

Friedman Billings Ramsey led the deal's underwriting.

On Friday the stock closed flat with the offering price at $6.75.

Alpha Natural Resources, Inc. (ANR: chart) priced 29.5 million shares at $19 per share, above the projected price range of $16 to $18. The Abington, Virginia-based coal miner raised $560.5 million via underwriters Morgan Stanley and Citigroup.

Alpha’s IPO enjoyed considerable interest from investors due to increasing coal prices and demand on the market.

On Friday the stock closed at $24.79 for a gain of $5.79, or 30.5%

The Sunrise, Florida-based online retailer of brand-name watches, fine jewelry and other luxury goods Odimo, Inc. (ODMO: chart) priced 3,125,000 shares of its common stock at a price of $9.00 per share, raising $27.9 million. The pricing came in at the low end of the expected $9 to $10 range.

CIBC World Markets led the deal's underwriting.

The company’s shares slid 0.44% to close at $8.96 on Friday.

Fusion Telecommunications International, Inc. (FSN: chart) priced 3,600,000 shares of common stock at $6.45 per share and 3,600,000 redeemable common stock purchase warrants at $0.05 per warrant.

Fusion Telecom provides VoIP and Internet services to markets in Asia, the Middle East, Africa, the Caribbean and Latin America.

The company’s shares climbed 19.4% to close at $7.70 on Friday.

The Cendant Corp. spin-off's Wright Express, Inc. (WXS: chart) IPO of 40 million shares priced at $18 on Tuesday, raising $720 million. Shares of South Portland, Maine-based company priced below the expected $19 to $21 range.

J.P. Morgan and CS First Boston led the deal's underwriting.